Table of Content

28 June 2024, Volume 13 Issue 2 Previous Issue    Next Issue

Commentary

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Treatment strategies for eyelid disease associated with thyroid eye disease WANG Huixue, YI Lan, JI Jiali, CHEN Qian, QIU Qinghua 2024, 13 (2):  91-95.  doi: 10.3969/j.issn.2095-378X.2024.02.001 Abstract ( 108 )   PDF (1200KB) ( 139 )   Save Thyroid eye disease （TED） is the most common orbital disease in adults, and it is an organ-specific autoimmune inflammation closely related to thyroid disease. The clinical manifestations of TED are complex, including abnormal eyelid position such as eyelid recession and ptosis in one or both eyes. Severe eyelid recession can lead to exposed corneal ulcers. For TED eyelid complications, drug or surgical treatment is performed according to disease progression to reconstruct the patient's ocular surface appearance and achieve anatomical and social function reduction. References | Related Articles | Metrics

Original article

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Expression and correlation of sFlt-1 and PlGF in placenta of patients with preeclampsia ZHOU Wenli, WANG Caili, KANG Wei, FENG Caixia 2024, 13 (2):  96-100.  doi: 10.3969/j.issn.2095-378X.2024.02.003 Abstract ( 105 )   PDF (1492KB) ( 187 )   Save Objective To investigate the expression and correlation of soluble FMS-like tyrosine kinase-1 （sFlt-1） and placental growth factor （PlGF） in placenta of patients with preeclampsia. Methods The maternal placenta during delivery and clinical data of 10 patients with preeclampsia （study group） and 12 normal pregnant women （control group） were collected and retrieved, who gave birth in our hospital from August 2021 to December 2022. The expression of sFlt-1 and PlGF in placental tissue was detected by Western blotting （WB）. Results Compared with the control group, there was no significant difference in the age and body mass index of pregnant women in the study group （P>0.05）. Urine protein was negative in the control group and positive in the study group. The gestational age and neonatal weight in the study group were significantly lower than those in the control group （P<0.01）. Systolic blood pressure and diastolic blood pressure in the study group were significantly higher than those in the control group （P<0.01）. WB detection showed that compared with the control group, the expression level of sFlt-1 in placental tissue of the study group was significantly higher than that of the control group （Z=–3.962, P<0.01）. The expression level of PlGF in the study group was significantly lower than that in the control group （Z=–3.957, P<0.01）. Conclusion The increase of anti-vascular factor sFlt-1 expression and the decrease of pro-angiogenic factor PlGF in placental tissue of preeclampsia patients abnormally regulate vasomotor contraction and relaxation and participate in the occurrence, development, and target organ damage of preeclampsia. References | Related Articles | Metrics

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Effect of ultrasound-mediated microwave ablation on thyroid related hormones in patients with benign thyroid nodules LI Wenfeng, TAN Xiaoming, OUYANG Qin, LI Zhihai 2024, 13 (2):  101-104.  doi: 10.3969/j.issn.2095-378X.2024.02.004 Abstract ( 72 )   PDF (1270KB) ( 152 )   Save Objective To explore the therapeutic effect of ultrasound-guided microwave ablation in patients with benign thyroid nodules and its impact on thyroid related hormones. Methods A total of 200 patients with benign thyroid nodules admitted from January 2020 to January 2023 were selected as study subjects. They were divided into two groups by random number table method, with 100 patients in each group. The control group received open surgery treatment, while the observation group received ultrasound-guided microwave ablation treatment. Treatment outcomes were evaluated in both groups, including surgical indicators, preoperative and postoperative 7 d inflammatory factors and thyroid related hormones, and incidence of postoperative complications and recurrence. Results The observation group had lower surgery time, hospital stay, intraoperative bleeding volumn, and hospitalization costs than the control group （P<0.05）. Both groups had varying degrees of inflammatory reactions 7 d after surgery, but the observation group showed lower levels of hypersensitive C-reactive protein （hs-CRP）, tumor necrosis factor-alpha （TNF-α）, epinephrine （E）, and norepinephrine （NE） than the control group （P<0.05）. Both groups had elevated levels of thyroid related hormones 7 d after surgery, but the levels of thyroid stimulating hormone （TSH）, serum free triiodothyronine （FT3）, and serum free thyroxine （FT4） in the observation group were lower than those in the control group （P<0.05）. The incidence rates of surgical complications, postoperative residuals, postoperative scars, and recurrence in the observation group were 2.00%, 2.00%, 1.00%, and 2.00%, respectively, which were lower than those in the control group （10.00%, 8.00%, 6.00%, and 8.00%, respectively） （P<0.05）. Conclusion Ultrasound-mediated microwave ablation is effective in treating patients with benign thyroid nodules, has advantages in reducing surgical trauma and postoperative complications, and has little impact on thyroid hormones and inflammatory factors, which is worth promoting and applying. References | Related Articles | Metrics

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Effects of different training intensities on cardiopulmonary function in patients with coronary heart disease after PCI ZHAO Yanmei, LUO Junting, LING Zheng, ZENG Chunmei, WANG Zhengdong 2024, 13 (2):  105-109.  doi: 10.3969/j.issn.2095-378X.2024.02.005 Abstract ( 75 )   PDF (1278KB) ( 165 )   Save Objective To investigate the effects of different training intensities on cardiopulmonary function in patients with coronary heart disease after percutaneous coronary intervention （PCI）. Methods A total of 100 patients with coronary heart disease who were hopitalized from July 2020 to February 2022 and successfully underwent PCI were selected and divided into a control group （50 cases） and a study group （50 cases） by random number table method. The control group （moderate intensity continuous training） had a maximum oxygen uptake （VO2） of 40% to 59% or a maximum heart rate of 55% to 69% as the training load, while the study group （high intensity interval training） had a maximum VO2 of >80% or a maximum heart rate of 85% to 95% as the training load. The two groups of patients exercised on an ergometer for 30 min per time, 3 times a week, for 4 consecutive weeks, and received conventional drug treatment. All patients underwent cardiac ultrasound and cardiopulmonary exercise test （CPET） before and after rehabilitation to evaluate cardiopulmonary function and exercise endurance. Results There were no significant differences in age, sex, and history of diseases between the two groups. Before rehabilitation, there were no significant differences in left ventricular ejection fractions （LVEF）, oxygen uptake at anaerobic threshold （VO2 AT）, peak oxygen uptake （peak VO2）, oxygen pulse, and ventilatory equivalent for carbon dioxide （VE/VCO2） slope between the study group and the control group. The changes before and after rehabilitation in VO2 AT, peak VO2, oxygen pulse, and minute ventilation volume （VE） were significantly higher in the study group than in the control group （P<0.05）. Spearman correlation analysis showed that the change values of VO2 AT, peak VO2, oxygen pulse, and VE were positively correlated with training intensity （P<0.05）. Conclusions Compared with moderate intensity continuous aerobic exercise, high intensity interval aerobic exercise can better improve the aerobic metabolic capacity and exercise endurance of patients with coronary heart disease after PCI. References | Related Articles | Metrics

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Impact of virtual reality technology on cognitive impairment and daily living ability of patients in rehabilitation treatment of hemiplegia after stroke GAO Hanlu, LIN Na 2024, 13 (2):  110-114.  doi: 10.3969/j.issn.2095-378X.2024.02.006 Abstract ( 134 )   PDF (1487KB) ( 170 )   Save Objective To explore the impact of virtual reality technology on cognitive impairment and daily living ability of patients in the rehabilitation treatment of hemiplegia after stroke. Methods A total of 80 patients with post-stroke hemiplegia who received treatment from September 2021 to March 2023 were selected as research subjects and randomly devided into two groups, namely the conventional group and the virtual technology group, with 40 cases in each group. The former received a conventional rehabilitation training plan, while the latter used virtual reality technology on the basis of the conventional rehabilitation training plan. The scores of the Montreal cognitive assessment scale （MoCA） and the activities of daily living （ADL） ability were compared between the two groups before and after 8 weeks of treatment. Results After the intervention, the MoCA and ADL scores of the virtual technology group were significantly higher than those of the conventional group （P<0.05）. Conclusion Virtual reality technology can effectively alleviate cognitive impairment and enhance patients' daily living abilities in the rehabilitation treatment of hemiplegia after stroke. References | Related Articles | Metrics

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Effect comparison of reconstruction of posterior cruciate ligament with autologous ipsilateral peroneus longus tendon and hamstring tendon autograft JIANG Dingjun, LI Jun, LU Xiao, ZHOU Mingjian, HOU Gang, HE Zhou, XU Yangjun 2024, 13 (2):  115-119.  doi: 10.3969/j.issn.2095-378X.2024.02.008 Abstract ( 67 )   PDF (7279KB) ( 134 )   Save Objective To use autologous ipsilateral peroneus longus tendon （PLT） reconstruction in patients with posterior cruciate ligament rupture, and compare with hamstring tendon （HT） reconstruction to analyze their safety and effectiveness. Methods A retrospective analysis was conducted on patients with posterior cruciate ligament rupture admitted to our hospital. The PLT group received autologous ipsilateral PLT reconstruction （22 cases）, while the HT group received autologous HT reconstruction （20 cases）. Observation indicators included perioperative conditions, follow-up indicators, and imaging evaluation. Results There were no statistically significant differences in selected perioperative indicators between the two groups of patients. The incidence of adverse reactions in the PLT group was significantly lower than that in the HT group. At the last follow-up, the knee joint score and imaging indicators of the PLT group were significantly better than those of the HT group. Conclusion The application of autologous ipsilateral PLT therapy in patients with posterior cruciate ligament injury reconstruction can efficiently restore knee joint function, alleviate pain symptoms, promote joint activity, and avoid the impact of surgical trauma on rehabilitation. References | Related Articles | Metrics

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Effect of emergency vascular interventional embolization in treatment of traumatic hemodynamically unstable pelvic fractures HUANG Guoliang, LI Jiangping, MAO Po, CAI Qinse, LI Hualiang, LIN Jinshi 2024, 13 (2):  120-124.  doi: 10.3969/j.issn.2095-378X.2024.02.015 Abstract ( 65 )   PDF (2295KB) ( 159 )   Save Objective To analyze the effect of emergency interventional vascular embolization in the treatment of hemodynamically unstable pelvic fractures. Methods A total of 124 patients with traumatic pelvic fractures and hemodynamic instability were enrolled in the study. There were 59 males and 65 females, with an average age of （33.5±2.8） years. Causes of injury： 76 cases of traffic accidents, 27 cases of falling from heights, and 21 other cases. According to different treatment methods, the patients were divided into a control group（n=61） using traditional conservative treatment and an observation group （n=63） using interventional vascular embolization. The hemodynamic indicators of the two groups of patients before and after surgery were compared. The operation time, intraoperative blood loss, hospitalization days, and complications were compared between the two groups. The Majeed pelvic fracture function score and the European quality of life-5 dimensions scale （EQ-5D） were used to evaluate the surgical efficacy and quality of life of the patients 3 months after surgery. Results There was no significant difference in general information between the two groups. The postoperative heart rate and blood lactate of the observation group decreased more significantly than those of the control group （P<0.001）; the postoperative systolic blood pressure and central venous pressure of the observation group were significantly increased compared with the control group（P<0.001）. At the follow-up one year after operation, the Majeed score and EQ-5D index of the control group and the observation group were significantly better than those before operation （P<0.05）. The Majeed score and the EQ-5D index of the observation group were significantly lower than those of the control group （P<0.001）. Conclusion Emergency vascular interventional embolization has a good effect on patients with traumatic hemodynamically unstable pelvic fractures, which provides good conditions for clinical rescue and treatment. References | Related Articles | Metrics

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Percutaneous endoscopic spinal decompression for lumbar spinal stenosis CHEN Jiyu, XU Gengtian, LI Zengyi, ZHUANG Huaiming 2024, 13 (2):  125-129.  doi: 10.3969/j.issn.2095-378X.2024.02.009 Abstract ( 72 )   PDF (1261KB) ( 131 )   Save Objective To investigate the effect of percutaneous endoscopic spinal decompression in patients with lumbar spinal stenosis. Methods A total of 90 patients with lumbar spinal stenosis from July 2021 to September 2023 were enrolled in the study. They were divided into two groups using a random number table method, with 45 patients in each group. The control group received conventional lumbar decompression surgery, while the observation group received percutaneous endoscopic spinal decompression surgery. The clinical efficacy, surgical indicators, pain scores, and Oswestry disability index （ODI） were compared between the two groups. Results After symptomatic treatment, the clinical efficacy of the two groups of patients improved significantly, and the observation group showed a higher effective rate than the control group （P<0.05）. The levels of surgical indicators （operation time and intraoperative blood loss volume） in the observation group were lower than those in the control group （P<0.05）, the hospital stay was shorter （P<0.05）, and the pain score and ODI values were lower （P<0.05）. Conclusion Percutaneous endoscopic spinal decompression has a significant effect on lumbar spinal stenosis, with significantly reduced pain levels and lighter lumbar dysfunction, which is beneficial for patient recovery. It can be used for reference and promotion in clinical practice. References | Related Articles | Metrics

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MR T2WI combined with DWI for preoperative staging of rectal cancer and its correlation with pathology WANG Chengli, DENG Na, YANG Cuiting, HAN Xiaobing, DU Kailing, PENG Weisheng 2024, 13 (2):  130-133.  doi: 10.3969/j.issn.2095-378X.2024.02.010 Abstract ( 104 )   PDF (1263KB) ( 149 )   Save Objective To study the value of magnetic resonance （MR） T2 weighted imaging （T2WI） combined with diffusion weighted imaging （DWI） in preoperative staging of rectal cancer and its correlation with pathology. Methods This retrospective analysis was conducted on 208 patients of rectal cancer with complete imaging and pathological data from June 2020 to June 2023. All patients underwent preoperative rectal standard protocol of MRI examination, with plain and enhanced scans indicating the location and size of the tumor and DWI signals measuring the apparent diffusion coefficient （ADC） value of the tumor. We compared the diagnostic efficacy of T2WI alone and the combination of T2WI and DWI, obtained the average and minimum ADC values of tumor tissues with different pathological grades, and analyzed the correlation between the two values and pathological grades. Results The diagnostic accuracy of combined T2WI and DWI for T2 and T3 stages of rectal cancer was significantly higher than that of T2WI alone （P<0.05）. The average and minimum ADC values of low differentiated rectal cancer were significantly lower than those of medium and high differentiated rectal cancers （P<0.05）, and the minimum ADC value was negatively correlated with pathological grade（r=–0.422, P<0.05）. Conclusions The combination of T2WI and DWI has a higher diagnostic efficiency for rectal cancer than T2WI alone. In addition, the minimum ADC value has a good value for preoperative pathological grading of tumors. References | Related Articles | Metrics

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Value of magnetic resonance multisequence imaging in guiding breast conserving surgery after neoadjuvant chemotherapy for triple negative breast cancer WU Xiaolan, WANG Junxiao 2024, 13 (2):  134-137.  doi: 10.3969/j.issn.2095-378X.2024.02.011 Abstract ( 57 )   PDF (1234KB) ( 131 )   Save Objective To investigate the value of magnetic resonance multisequence imaging in guiding breast conserving surgery after neoadjuvant chemotherapy for triple negative breast cancer （TNBC）. Methods A total of 98 patients with TNBC admitted to Sanming Second Hospital in Fujian Province from June 2018 to June 2023 （all receiving neoadjuvant chemotherapy） were selected and randomly divided into a control group and an observation group by random number method. Among them, 49 patients underwent ultrasound body surface localization and were included in the control group, and the other 49 patients underwent magnetic resonance multisequence imaging and were included in the observation group. Both groups underwent breast conserving surgery to compare the application value of different imaging techniques for the surgery. Results The preoperative estimated maximum diameter of the tumor and the tumor/breast volume in the observation group were smaller than those in the control group （P<0.01, P<0.05）, and the coincidence rate with the actual surgical resection of the tumor volume and the negative margin rate in the observation group were higher than those in the control group （P<0.05）. There was no difference in surgical time and incidence of complications between the observation group and the control group （P>0.05）. Conclusion Magnetic resonance multisequence imaging has an important value in guiding breast conserving surgery in TNBC patients after neoadjuvant chemotherapy, providing an accurate resection range, and having a low incidence of complications, which is worth promoting. References | Related Articles | Metrics

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Effects of sevoflurane inhalation anesthesia on cognitive function and postoperative delirium in elderly patients undergoing minimally invasive surgery LIANG Huana, CHEN Dequan, LIN Baoliu 2024, 13 (2):  138-141.  doi: 10.3969/j.issn.2095-378X.2024.02.012 Abstract ( 79 )   PDF (1260KB) ( 151 )   Save Objective To observe the effects of sevoflurane inhalation anesthesia on cognitive function and postoperative delirium after minimally invasive surgery in elderly patients. Methods A total of 80 elderly patients who underwent laparoscopic cholecystectomy in Yangjiang People's Hospital from October 2022 to October 2023 were selected as study subjects. According to the random number table method, they were divided into an observation group （sevoflurane inhalation anesthesia） and a control group （propofol pump injection anesthesia）, with 40 patients in each group. The serum central nervous system specific protein （S100β） level was detected before and after surgery; the cognitive function was evaluated using the mini-mental state examination （MMSE） and the Montreal cognitive assessment （MoCA） before and after surgery; the postoperative delirium was determined according to the confusion assessment method （CAM） score, and the incidence of postoperative delirium was calculated. The differences in the above observation indicators were compared between the two groups. Results After surgery, the S100β level in the observation group was significantly lower than that in the control group （P<0.05）. The postoperative cognitive function scores （MMSE and MoCA scores） in the observation group were significantly higher than those in the control group （P<0.05）. The incidence of postoperative delirium in the observation group was 5.00%, lower than 10.00% in the control group, but the difference between the groups showed no statistically significance （P>0.05）. Conclusion Sevoflurane inhalation anesthesia has a protective effect on central nervous cells, which can effectively reduce the impact on cognitive function after minimally invasive surgery in elderly patients, and will not increase the incidence of postoperative delirium. References | Related Articles | Metrics

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Clinical efficacy of selective cervical nerve block combined with myofascial trigger point inactivation in treatment of cervical spondylotic radiculopathy WANG Yafeng 2024, 13 (2):  142-145.  doi: 10.3969/j.issn.2095-378X.2024.02.013 Abstract ( 79 )   PDF (1246KB) ( 149 )   Save Objective To observe the clinical efficacy of selective cervical nerve block combined with myofascial trigger point inactivation in the treatment of cervical spondylotic radiculopathy （CSR）. Methods Sixty CRS patients visiting the pain clinic at Songjiang District Sijing Hospital between March and September 2023 were randomly divided into three groups by random number table method, with 20 cases in each group. The treatment group （group A） received selective cervical nerve root and posteromedial branch block combined with myofascial trigger point inactivation treatment, the control group 1 （group B） received selective cervical nerve root and posteromedial branch block alone, and the control group 2 （group C） was treated with cervical traction and drugs. The patients were followed up at 1, 4, and 12 weeks after treatment for efficacy evaluation. The visual analogue scale （VAS） scores of neck and upper limb and the neck disability index （NDI） were compared across three groups. Results （1）Intra-group comparison revealed significant decreases in the VAS and NDI scores 1, 4, and 12 weeks after treatment in all groups （P<0.01）. （2） Pairwise comparison revealed that group A and group B consistently showed significantly lower VAS and NDI scores than group C at selected post-treatment time points （P<0.05）. Notably, group A exhibited significantly lower VAS and NDI scores than group B at the 12th week （P<0.05）, indicating a superior long-term effect. Conclusion The combined approach of myofascial trigger point inactivation and selective cervical nerve block for treating CRS demonstrates a synergistic effect, characterized by both rapid and sustained efficacy. References | Related Articles | Metrics

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Effect of remazolam benzenesulfonate anesthesia on hemodynamics in elderly patients undergoing painless gastrointestinal microscopy CAI Zhangxi 2024, 13 (2):  146-149.  doi: 10.3969/j.issn.2095-378X.2024.02.014 Abstract ( 84 )   PDF (1237KB) ( 149 )   Save Objective To investigate the effect of remazolam benzenesulfonate anesthesia on hemodynamics in elderly patients undergoing painless gastroenteroscopy. Methods A total of 100 patients with painless gastroenteroscopy in Jin'an Distric Hospital of Fuzhou City from January 2021 to June 2023 were selected and divided into a control group and a study group with 50 cases in each group by random number table method. The control group was anesthetised with propofol + afentanil, and the study group was anesthetised with remazolam benzenesulfonate + afentanil. The hemodynamics and anesthesia quality of the two groups were compared at different time points [before anesthesia induction （T0）, 3 min of anesthesia induction （T1）, 10 min of anesthesia induction （T2）, and recovery （T3）]. Results Compared with T0, the heart rate, blood oxygen saturation, and mean arterial pressure of patients at T1-T3 decreased, but the three indicators of patients in the study group decreased less than those of the control group, and at T3, the three indicators of patients in the two groups rebounded （P<0.05）. The onset time of induction in the study group was longer than that in the control group, and the time of awakening and leaving the surgery room was shorter than that in the control group （P<0.05）. Conclusion Actively implementing remazolam benzenesulfonate + alfentanil anesthesia during painless gastroenteroscopy in elderly patients can achieve ideal anesthesia effects and have less impacts on hemodynamics. References | Related Articles | Metrics

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Comparison of effects of different hysteroscopic surgeries on endometrial polyps with abnormal uterine bleeding ZOU Lili, ZHONG Ping, DAI Yajuan 2024, 13 (2):  150-153.  doi: 10.3969/j.issn.2095-378X.2024.02.016 Abstract ( 79 )   PDF (1264KB) ( 130 )   Save Objective To explore the long-term effects of different hysteroscopic surgeries in the treatment of endometrial polyps combined with abnormal uterine bleeding, analyze the effect of hysteroscopic cold knife resection on uterine arterial blood flow parameters and hemoglobin in patients, and provide new ideas for improving clinical efficacy. Methods According to the random number table method, 80 patients with endometrial polyps and abnormal uterine bleeding admitted from January 2020 to June 2023 were divided into a reference group and a study group （40 cases in each group）, and hysteroscopic electroresection and hysteroscopic cold knife resection were performed respectively. Endometrial thickness, uterine arterial blood flow parameters, and hemoglobin levels before and after surgery were compared between the two groups. The patients were followed up for 6 months after surgery, and the incidence rates of postoperative complications, recurrence of uterine polyps, and abnormal uterine bleeding in the two groups were recorded. Results At 1, 3, and 6 months after surgery, the patients in the study group had less endometrial thickness than the reference group （P<0.05）. At 6 months after surgery, the blood flow resistance index （RI） and pulsatility index （PI） of the study group were lower than those of the reference group, and the hemoglobin level was higher （P<0.05）. The postoperative complication rate in the study group was 5.00%, which was lower than 22.50% in the reference group, and the difference was statistically significant （P<0.05）. The recurrence rate of postoperative endometrial polyps and the incidence rate of abnormal uterine bleeding were lower in the study group than in the reference group （P<0.05）. Conclusion Hysteroscopic cold knife resection of endometrial polyps can effectively reduce endometrial hyperplasia, improve uterine blood circulation, restore hemoglobin level, and have fewer postoperative complications, so the long-term effect on preventing recurrence of endometrial polyps and abnormal uterine bleeding is ideal. References | Related Articles | Metrics

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Improvement effect of intralesional separation combined with carbon dioxide lattice laser on pigmentation and scar area in patients with facial depressed scars GAO Shangyan 2024, 13 (2):  154-157.  doi: 10.3969/j.issn.2095-378X.2024.02.017 Abstract ( 69 )   PDF (1236KB) ( 159 )   Save Objective To observe the improvement effect of intralesional separation combined with carbon dioxide lattice laser on pigmentation and scar area in the treatment of facial depressed scars. Methods The clinical data of 76 patients with facial depressed scars from November 2020 to September 2023 were retrospectively analyzed. They were divided into a control group and an observation group with 38 cases in each group. The patients in the control group were treated with carbon dioxide lattice laser, while the patients in the observation group were treated with intra-scar separation combined with carbon dioxide lattice laser. The before-and-after pigmentation and scar area and incidence of complications of the two groups were compared. Results After treatment, the pigmentation and scar area of the observation group were smaller than those of the control group （P<0.05）; the difference in the incidence of complications between the two groups was not statistically significant （P>0.05）. Conclusion Intralesional separation combined with carbon dioxide lattice laser has a good effect in the treatment of facial depressed scars, which is superior to the treatment with carbon dioxide lattice laser alone. It can significantly reduce the facial pigmentation and scar area of patients, and does not significantly increase the incidence of complications. References | Related Articles | Metrics

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A comparative analysis of clinical effects of minimally invasive puncture and drainage of hematoma and traditional craniotomy on hypertensive intracerebral hemorrhage WANG Zhiqiang, ZHANG Jiaying 2024, 13 (2):  158-161.  doi: 10.3969/j.issn.2095-378X.2024.02.018 Abstract ( 56 )   PDF (1261KB) ( 151 )   Save Objective To explore the clinical values of minimally invasive puncture and drainage of hematoma and traditional craniotomy in the treatment of hypertensive intracerebral hemorrhage （HIH）. Methods A total of 41 patients with HIH treated with minimally invasive puncture and drainage of hematoma from January 2017 to December 2022 were selected as Mi group, and at the same time, 46 patients with HIH treated with traditional craniotomy were selected as Tc group. The hematoma clearance rate, nerve injury, self-care ability, quality of life, and adverse reactions of the two groups were compared. Results There was no significant difference in the clearance rate of hematoma between the two groups （P>0.05）. The incidence of adverse reactions in the Mi group was significantly lower than that in the Tc group （P<0.05）. The National Institutes of Health stroke scale （NIHSS）, activities of daily living （ADL）, and short form health survey （SF-36） scores were not significantly different between the two groups before operation （P>0.05）, but were significantly improved in the two groups after operation （P<0.05）, and the scores of NIHSS, ADL, and SF-36 in the Mi group were significantly better than those in the Tc group （P<0.05）. Conclusion Compared with traditional craniotomy, minimally invasive puncture and drainage of hematoma can significantly reduce the incidence of postoperative complications and improve the long-term prognosis of patients with HIH. References | Related Articles | Metrics

Education and management on public health

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Application of PBL combined with CBL teaching mode in teaching of diagnosis and treatment of heart valvular disease for trainees YUE Honghua, FANG Zhi 2024, 13 (2):  162-165.  doi: 10.3969/j.issn.2095-378X.2024.02.019 Abstract ( 72 )   PDF (1255KB) ( 83 )   Save Objective To explore the application of problem-based learning （PBL） combined with case-based learning （CBL） teaching mode in the teaching of diagnosis and treatment of heart valvular disease for trainees. Methods A total of 64 clinical medical students who received standardized residency training from February 2017 to February 2024 were included and divided into a test group and a control group by random number table method, with 32 students in each group. The relevant teaching data of the two groups were compared and analyzed. Results The test group's theoretical scores （89.76±0.41） and practical skill scores （91.42±0.78） were significantly higher than those of the control group （82.34±0.78 and 81.68±1.63） （P<0.05）. The scores of the test group in teaching content, teaching method, teaching effect, teaching ability, and teaching attitude were higher than those of the control group （P<0.05）. Conclusion The teaching mode of PBL combined with CBL can not only enhance students' understanding of clinical teaching content including theoretical knowledge and practical skills, but also improve their ability to find and solve problems, which effectively improve their doctor-patient communication ability. References | Related Articles | Metrics

Nursing

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Development and application of nursing training program for malignant hyperthermia in perioperative patients GUAN Lina, ZHANG Yayun, ZHANG Di, GUO Ya, JIN Jie 2024, 13 (2):  166-170.  doi: 10.3969/j.issn.2095-378X.2024.02.020 Abstract ( 69 )   PDF (1291KB) ( 135 )   Save Objective To explore the application effect of a nursing training program for malignant hyperthermia in perioperative patients. Methods From October to November 2023, a total of 72 anesthesia nurses at The First Affiliated Hospital of Zhengzhou University of Henan Province were divided into two groups for training. The experimental group （36 subjects） used the training program for malignant hyperthermia in perioperative patients, and the training outline was developed around seven modules; the control group （36 subjects） adopted the conventional multimedia theory lecture and video demo teaching mode. The nursing ability scores of perioperative malignant hyperthermia, theoretical assessment scores, and evaluation of training effect were compared between the two groups. Results The scores of nursing ability of perioperative malignant hyperthermia, the scores of theoretical assessment, and the scores of training effect evaluation in the experimental group were all significantly higher than those in the control group （P<0.05）. Conclusion The nursing training program for malignant hyperthermia in perioperative patients helps to improve nursing ability of anesthesia nurses and enhance the training effect and training quality. References | Related Articles | Metrics

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Effect of comprehensive postoperative recovery plan combined with systemic respiratory training on patients undergoing pulmonary nodule surgery LI Qinqin, CHEN Fengyu, QIU Fengying, ZHANG Huizhen 2024, 13 (2):  171-174.  doi: 10.3969/j.issn.2095-378X.2024.02.021 Abstract ( 85 )   PDF (1267KB) ( 141 )   Save Objective To explore the effect of a comprehensive postoperative recovery plan combined with systemic respiratory training in patients undergoing pulmonary nodule surgery. Methods According to the random number table method, 175 patients who underwent pulmonary nodule surgery in the 910 Hospital of Joint Logistics Support Force from June 2019 to August 2022 were divided into two groups： the control group of 87 patients received comprehensive postoperative recovery intervention, and the observation group of 88 patients received systemic respiratory training on the basis of the control group. Clinical indicators, respiratory function, pulmonary function, and incidence of complications were observed and compared between the two groups of patients. Results After the intervention, the observation group had shorter first exhaust time, first defecation time, out-of-bed time, drainage tube retention time, and hospitalization time than the control group （P<0.05）. The respiratory frequency and the Borg fatigue scale score after intervention in the observation group were lower than those in the control group （P<0.05）. The forced vital capacity （FVC）, forced expiratory volume in 1 s （FEV1）, and FEV1/FVC of the observation group after intervention were all higher than those of the control group （P<0.05）. The incidence of complications in the observation group was lower than that in the control group （P<0.05）. Conclusion The comprehensive postoperative recovery plan combined with systemic respiratory training can improve lung function and respiratory function, reduce the incidence of complications, and shorten postoperative recovery time in patients undergoing pulmonary nodule surgery. References | Related Articles | Metrics

Case report

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Emergency percutaneous coronary intervention combined with extracorporeal membrane oxygenation for acute ST-segment elevation myocardial infarction： A case report JIANG Jun, TANG Yun, ZHANG Ying, ZHAO Yanchao, LIU Chi 2024, 13 (2):  175-178.  doi: 10.3969/j.issn.2095-378X.2024.02.022 Abstract ( 60 )   PDF (1183KB) ( 138 )   Save Acute ST-segment elevation myocardial infarction （STEMI） is one of the serious types of coronary heart disease. Early and rapid opening of infarction related arteries by interventional means is the key to improving prognosis. Some patients with acute STEMI are prone to cardiogenic shock, which makes interventional therapy impossible. Extracorporeal membrane oxygenation （ECMO） can improve the safety and effectiveness of interventional therapy by supporting respiratory and circulatory functions. This paper reported a case of acute STEMI successfully treated by emergency percutaneous coronary intervention combined with ECMO, and discussed how to improve the success rate of acute STEMI, especially in patients with cardiogenic shock. References | Related Articles | Metrics

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Cause analysis and reflection on one missed diagnosis case of elderly pneumonia complicated with pulmonary embolism BAI Daoliang 2024, 13 (2):  179-180.  doi: 10.3969/j.issn.2095-378X.2024.02.023 Abstract ( 69 )   PDF (1043KB) ( 86 )   Save Pulmonary embolism has a hidden onset, lacks specific symptoms, and is often masked by accompanying diseases, resulting in a generally high rate of missed diagnosis in clinical practice. This paper discussed the clinical data of a missed diagnosis case of elderly pneumonia complicated with pulmonary embolism, and analysed the causes for the missed diagnosis. References | Related Articles | Metrics