Table of Content

28 September 2025, Volume 14 Issue 3 Previous Issue   

Commentary

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Mechanical removal of deep vein thrombosis of lower extremity： Development, controversy, and future prospects WANG Xuhui, ZUO Liang, YIN Minyi 2025, 14 (3):  199-203.  doi: 10.3969/j.issn.2095-378X.2025.03.001 Abstract ( 29 )   PDF (1272KB) ( 25 )   Save Deep vein thrombosis （DVT） of the lower extremity is a common and serious condition in vascular surgery, and can lead to fatal pulmonary embolism （PE） and post-thrombotic syndrome （PTS）, severely affecting quality of life. Although traditional anticoagulation therapy serves as the cornerstone, it has limited efficacy in removing established thrombi. Consequently, the incidence of PTS remains persistently high （20%‒50%）. Furthermore, for patients with extensive iliofemoral vein thrombosis （e.g., phlegmasia cerulea dolens）, anticoagulation alone is insufficient to prevent high-risk limb gangrene. Catheter-directed thrombolysis （CDT） has shown promise, but pivotal studies （e.g., the ATTRACT trial） have demonstrated that it fails to significantly reduce the incidence of long-term PTS and increases the risk of bleeding. Percutaneous mechanical thrombectomy （PMT）, as an innovative physical thrombectomy technology, has developed rapidly over the past decade. New and efficient devices have emerged and have been recommended by domestic and international guidelines. Based on the background, core advantages, and guideline positioning of PMT technology, this paper systematically reviewed the technical principles, clinical evidence, and safety characteristics of mainstream PMT devices. It analyzed the key challenges currently faced, focused on their future development prospects, and proposed directions that need to be urgently addressed, such as intelligent precision, efficiency improvement, cost control, and high-quality evidence-based research. References | Related Articles | Metrics

Original article

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Role and mechanism of miR-21-5p in early adverse life events inducing irritable bowel syndrome ZHANG Haiqin, HAN Bo, ZHOU Lu, CHU Yimin, XU Ying, PENG Haixia 2025, 14 (3):  204-210.  doi: 10.3969/j.issn.2095-378X.2025.03.002 Abstract ( 18 )   PDF (4104KB) ( 7 )   Save Objective To investigate the role of miR-21-5p in early adverse life events （EALs）-induced visceral hypersensitivity of irritable bowel syndrome （IBS） and its mechanism. Methods A rat model of visceral hypersensitivity induced by EALs in adult rats was established by mother-infant separation. MicroRNA （miRNA） microarrays combined with quantitative polymerease chain reaction （qPCR） were used to screen for differential miRNAs in dorsal root ganglion （DRG） neurons, and bioinformatics analysis combined with luciferase reporter gene assay was performed to search for downstream targets of the differential miRNAs. Cellular and animal experiments were combined to verify if the differential miRNAs were involved in mother-infant separation-induced visceral hypersensitivity through the downstream targets. Results MiR-21-5p was significantly overexpressed in the DRG neurons of mother-infant separation-induced adult visceral hypersensitivity rats （P<0.05）. Bioinformatics analysis, luciferase reporter gene assay, and cellular experiments suggested that transforming growth factor beta induction （TGFBI） gene was a miR-21-5p target gene. At the cellular level, the TGFBI protein level in DRG neurons was significantly decreased after miR-21-5p mimic intervention （P<0.05）, and significantly increased after miR-21-5p inhibitor intervention （P<0.05）. At the animal level, the visceral sensitivity was significantly higher （P<0.05） and TGFBI protein level was significantly lower （P<0.05） in rats after miR-21-5p agonist intervention compared with the control group,and visceral sensitivity was significantly lower （P<0.05） and the TGFBI protein level was significantly higher （P<0.05） in rats after miR-21-5p antagonist intervention compared with the control group. Conclusion MiR-21-5p in rat DRG promotes mother-infant separation-induced visceral hypersensitivity by inhibiting TGFBI expression, and thus participates in the development of adult IBS induced by EALs. References | Related Articles | Metrics

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Risk factors for hypocalcemia after thyroid nodule resection HUO Jianting, HUO Huanmin, DING Min, XIE Rongli, SHEN Dongjie, FEI Jian 2025, 14 (3):  211-215.  doi: 10.3969/j.issn.2095-378X.2025.03.003 Abstract ( 24 )   PDF (1334KB) ( 16 )   Save Objective To study the risk factors of postoperative hypocalcemia after resection of thyroid nodules. Methods A retrospective study was conducted on 124 patients undergoing thyroid nodule resection surgery, including age, gender, mass nature, lesion location （unilateral/bilateral）, lymph node dissection, surgical approach, perioperative blood calcium （adjusted and un-adjusted）, parathyroid hormone （PTH）, and blood magnesium. Patients were divided into a hypocalcemia group and a non-hypocalcemia group based on their postoperative blood calcium levels, to compare the differences between the two groups and thereby investigate the risk factors for hypocalcemia after thyroid nodule resection. Results Of the 124 cases enrolled, 12 cases （9.7%） developed hypocalcemia after the operation, with an average blood calcium of （2.10±0.08） mmol/L. After albumin correction of blood calcium level, 9 cases （7.3%） had hypocalcemia, with an average blood calcium of （2.05±0.14） mmol/L. There were no statistically significant differences between the two groups stratified by corrected blood calcium levels in terms of age, gender, mass nature, and performance of lymph node dissection （P> 0.05）. However, significant differences were observed in lesion location （unilateral/bilateral）, surgical approach, average postoperative PTH level, and presence of postoperative hypomagnesemia （P<0.05）. Conclusion For patients with postoperative hypoproteinemia, corrected blood calcium levels should be used to evaluate whether the patient needs additional calcium supplementation. Surgical procedure is a high-risk factor for postoperative hypocalcemia, and postoperative hypomagnesemia and postoperative PTH reduction are associated with hypocalcemia. References | Related Articles | Metrics

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Short-term efficacy of laparoscopic sleeve gastrectomy on glucose and lipid metabolism disorders in obese patients with diabetes and non-alcoholic fatty liver disease LIANG Guanyou, LI Tao 2025, 14 (3):  216-220.  doi: 10.3969/j.issn.2095-378X.2025.03.004 Abstract ( 21 )   PDF (1309KB) ( 13 )   Save Objective To observe the short-term effects of laparoscopic sleeve gastrectomy on glucose and lipid metabolism disorders in obese patients with diabetes and non-alcoholic fatty liver disease. Methods A retrospective analysis was conducted on 130 patients who underwent laparoscopic sleeve gastrectomy from January 2020 to December 2023. Based on the hospital's electronic medical record system, the patients were followed up for 6 months after surgery. Patient's preoperative and postoperative 3 and 6 months physical signs [body weight, body mass index （BMI）, and waist circumference], glucose metabolism indicators （glycated hemoglobin, fasting blood glucose, 2-hour postprandial blood glucose, pancreatic beta cell function index, and insulin resistance index）, blood lipids （total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and triglycerides）, and liver function indicators （aspartate aminotransferase, and alanine aminotransferase） were recorded and calculated. Results As of the last follow-up, 12 patients were lost to follow-up, and the remaining 118 patients successfully completed follow-up, with a follow-up rate of 90.77%. Patients' weight, BMI, waist circumference, glycated hemoglobin, fasting blood glucose, 2-hour postprandial blood glucose, pancreatic beta cell function index, insulin resistance index, total cholesterol, low-density lipoprotein cholesterol, triglycerides, aspartate aminotransferase, and alanine aminotransferase showed a decreasing trend over time after surgery, while high-density lipoprotein cholesterol showed an increasing trend. Compared with preoperative levels, there were statistically significant differences in physical signs, glucose metabolism, blood lipids, and liver function indicators at 3 and 6 months after surgery （P<0.05）. Postoperatively, a total of 7 patients developed incision infection and 1 patient developed abdominal infection, with an overall incidence of postoperative adverse events of 6.15% （8/130）. Conclusion Laparoscopic sleeve gastrectomy can help obese patients control their weight and improve blood glucose and lipid homeostasis. References | Related Articles | Metrics

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Clinicopathological features, treatment regimens, and efficacy analysis of 217 cases of epulis LIN Liangqin, LIN Pingting 2025, 14 (3):  221-225.  doi: 10.3969/j.issn.2095-378X.2025.03.005 Abstract ( 23 )   PDF (1392KB) ( 17 )   Save Objective To investigate the clinicopathological features of epulis and its histopathological subtypes and evaluate the outcomes of different excision methods （scalpel, electrotome, or laser） on the prognosis of epulis. Methods A total of 217 cases of epulis were retrospectively analyzed between August 2021 to July 2024. Gender, age, tumor location, size, symptoms of periodontitis at first visit, excision method, tooth extraction, and root planning during surgery were derived from medical records. Recurrence information was used to evaluate outcomes of different treatment regimens. Results The average age of the patients in this study was （40.25±11.32） years, with a common age range of 20‒40 years. Among them, 134 （61.75%） were female patients and 83 （38.25%）were male patients; epulis was significantly more common in females （χ2=11.986, P<0.001）. There were 130 cases （59.91%） of epulis located in the anterior tooth area and 87 cases （40.09%） in the posterior tooth area, and the proportion of anterior tooth area was significantly higher than that of posterior tooth area for epulis （χ2=10.594, P=0.014）. Histopathologically, the incidence rate from high to low was epulis fibromatosa （69.59%）, epulis granulomatosa （21.20%）, peripheral ossifying fibroma （8.29%）, and giant cell epulis （0.92%）. From the perspective of recurrence, the method of epulis resection, whether the affected tooth was removed, and whether there was periodontitis before surgery had no significant effects on recurrence （P>0.05）. However, the patients receiving root planing during surgery had a significantly lower incidence of recurrence than those who did not （χ2=7.814, P=0.018）. Conclusion Epulis is common in women and in the anterior tooth area, and fibrous hyperplasia is dominant in histopathological subtypes. When concerning treatment regimens, removal methods and tooth extraction would not interfere with recurrence. Root planing during surgery might help reduce the recurrence of epulis. References | Related Articles | Metrics

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Influencing factors for perioperative hidden blood loss of femoral intertrochanteric fractures DAI Yahui, QIN Tao, SUN Yan 2025, 14 (3):  226-229.  doi: 10.3969/j.issn.2095-378X.2025.03.006 Abstract ( 19 )   PDF (1297KB) ( 24 )   Save Objective To study the influencing factors of perioperative hidden blood loss of femoral intertrochanteric fractures and explore the risk factors for clinical intervention （in-hospital blood transfusion） using retrospective analysis. Methods Data of patients with intertrochanteric fracture admitted to our hospital from 2020 to 2022 were retrospectively analyzed. Their gender, age, height, weight, comorbidities, preoperative and postoperative blood routine test results, postoperative complications, surgical methods, operation time, intraoperative blood loss, and blood transfusion were retrieved, and grouped accordingly. A t-test was used to analyze the amount of blood loss between different groups, and a binary logistic regression was used to evaluate the risk factors for in-hospital blood transfusion secondary to perioperative hidden blood loss in patients. Results A total of 274 patients were retrospectively analyzed, including 125 males and 149 females, 151 cases with left fracture and 123 cases with right fractue. All of the patients were treated by surgery without serious complications. The average operation time was （65.16±23.61） min, the total blood transfusion volume was （386±293） mL, the total blood loss volume was （862±477） mL, of which the average hidden blood loss volume was （753±444） mL, and the average hospitalization was （12.77±4.69） d. Unstable fracture （Evans Ⅲ-Ⅳ） was an influencing factor for increased hidden blood loss （P<0.05）. Age, body mass index, and comorbidities had no significant effect on total blood loss or hidden blood loss volume. Long operative time and low preoperative hemoglobin level were main risk factors for blood transfusion secondary to perioperative hidden blood loss （P<0.05）. Conclusion Unstable fracture is an influencing factor for hidden blood loss during perioperative femoral intertrochanteric fractures, and long operation time and low preoperative hemoglobin level are risk factors for in-hospital blood transfusion secondary to perioperative hidden blood loss. References | Related Articles | Metrics

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A dose-response relationship study of oliceridine combined with propofol for gastrointestinal endoscopy HUANG Guangyong, HUANG Minzhen, LIU Baoyun 2025, 14 (3):  230-233.  doi: 10.3969/j.issn.2095-378X.2025.03.007 Abstract ( 20 )   PDF (1371KB) ( 35 )   Save Objective To determine the median effective dose （ED50） and 95% effective dose （ED95） of oliceridine combined with propofol （plasma target-controlled concentration at 3 μg/mL） for painless gastrointestinal endoscopy. Methods A total of 27 patients scheduled for painless gastrointestinal endoscopy from July to December 2024 were enrolled. All patients received propofol via target-controlled infusion （TCI） at a plasma concentration of 3 μg/mL. The modified Dixon's up-and-down sequential method was used to determine the oliceridine dose （initial dose 1 mg,step size 0.1 mg）. The dose for each subsequent patient was adjusted based on the response of the previous patient （positive response： coughing, retching, or purposeful movement during endoscopy）, with an increase after a positive response and a decrease after a negative response. The study was terminated after 7 response crossovers. Probit regression analysis was used to calculate the ED50, ED95, and their 95% confidence intervals （CIs） for oliceridine. Results The ED50 of oliceridine combined with propofol （TCI 3 μg/mL） for gastrointestinal endoscopy was 0.829 mg （95%CI 0.509-1.053 mg）, and the ED95 was 1.176 mg （95%CI 0.997-4.936 mg）. Conclusion When oliceridine is combined with propofol （TCI 3 μg/mL） for gastrointestinal endoscopy, the ED95 of oliceridine to suppress the insertion response is 1.176 mg. This provides a dose reference for clinical application. References | Related Articles | Metrics

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Prognosis and family acceptability of microscopic small bone window craniotomy hematoma removal and hard channel puncture hematoma drainage in treatment of hypertensive intracerebral hemorrhage of elderly patients CAI Yesheng, HU Xitian 2025, 14 (3):  234-237.  doi: 10.3969/j.issn.2095-378X.2025.03.008 Abstract ( 19 )   PDF (1294KB) ( 19 )   Save Objective To compare the effects of microscopic small bone window craniotomy hematoma removal and hard channel puncture hematoma drainage on the prognosis and family acceptance of elderly hypertensive intracerebral hemorrhage （HICH）. Methods A total of 100 elderly patients with HICH admitted from January 2021 to April 2024 were selected as research subjects, and randomly divided into a hard channel puncture group （hard channel puncture hematoma drainage） and a bone window craniotomy group （microscopic small bone window craniotomy hematoma removal）, with 50 cases in each group. The effects of the two groups and the acceptance of surgery of family were compared and analyzed. Results The operation time and hospital stay in the hard channel puncture group were significantly shorter than those in the bone window craniotomy group （P<0.05）, and the clearance rate of hematoma and Glasgow outcome scale （GOS） score were significantly higher （P<0.05）. The incidence of postoperative complications in the hard channel puncture group was significantly lower than that in the bone window craniotomy group （P<0.05）. The surgical acceptance of patients' family members of the hard channel puncture group was significantly higher than that of the bone window craniotomy group （P<0.05）. There were no significant differences in the scores of Glasgow coma scale （GCS）, activity of daily living （ADL）, and short form 36 （SF-36） between the two groups before surgery （P>0.05）. At postoperative 3 months, the scores of GCS, ADL, and SF-36 between the two groups were significantly improved （P<0.05）, and the scores in the hard channel puncture group were significantly better than those in the bone window craniotomy group （P<0.05）. Conclusion In consideration of the characteristics of the HICH patients group, hard channel puncture drainage is a good choice for the families of patients who are unwilling to undergo craniotomy due to its advantages of short hospital stay and small trauma, and can be promoted in specific populations. References | Related Articles | Metrics

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Efficacy of minimally invasive arthroscopic Kirschner wire tension banding in treatment of patella fracture and factors associated with postoperative complications LIU Haixin, LU Jianqi, CAI Zhongbin, WANG Quan, WANG Zemin, WANG Haiwen, XU Xianglin, LU Jiongwen 2025, 14 (3):  238-242.  doi: 10.3969/j.issn.2095-378X.2025.03.009 Abstract ( 19 )   PDF (7508KB) ( 13 )   Save Objective To investigate the efficacy of minimally invasive Kirschner wire tension band internal fixation under arthroscopy for the treatment of patellar fractures and analyze the factors related to postoperative complications. Methods Sixty patients with patellar fractures treated in the Orthopedic Department from January 2021 to January 2025 were selected as research subjects. The patients were randomly divided into a control group and a study group, with 30 cases in each group. The control group received open reduction and Kirschner wire tension band internal fixation treatment, while the study group received minimally invasive Kirschner wire tension band internal fixation treatment under arthroscopy. Fracture healing time, knee joint range of motion, knee joint function （Bostman score）, daily living ability （Barthel index, BI）, quality of life （life satisfaction index A scale, LISA）, pain score （visual analog scale, VAS）, and postoperative complications were compared between the two groups after treatment. Univariate and multivariate logistic regression analyses were conducted on factors related to the complications. Results After treatment, the fracture healing time of the study group was significantly shorter than that of the control group, and the improvement of knee joint range of motion and knee joint function was better than that of the control group （P<0.05）. After treatment, the BI and LISA scores of the study group were significantly higher than those of the control group, and the VAS scores were significantly lower （P<0.05）. The incidence of complications in the study group was 3.33% （1/30）, which was significantly lower than 20.00% （6/30） in the control group （P<0.05）. Univariate analysis showed that age ≥ 60 years, open surgery, and fracture healing time ≥100 d were potential factors associated with postoperative complications （P<0.05）. Multivariate logistic regression analysis showed that age ≥60 years （OR=5.236）, open surgery （OR=6.814）, and fracture healing time ≥ 100 d （OR=4.937） were independent risk factors for complications （P<0.05）. Conclusion Minimally invasive Kirschner wire tension band internal fixation under arthroscopy has significant advantages in the treatment of patellar fractures, which can effectively shorten fracture healing time, improve knee joint function and motion, enhance patients' daily living ability and quality of life, and its incidence of postoperative complications is significantly lower than that of traditional open surgery. Older age, traditional open surgery, and longer fracture healing time are independent risk factors for postoperative complications, which should be taken seriously in clinical practice. References | Related Articles | Metrics

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Curative effect of percutaneous foraminoscopic extraction of nucleus pulposus on lumbar disc herniation LUO Zhiqiang, WANG Yanghua, WU Jianshun 2025, 14 (3):  243-247.  doi: 10.3969/j.issn.2095-378X.2025.03.010 Abstract ( 17 )   PDF (2813KB) ( 31 )   Save Objective To investigate the effect of percutaneous intervertebral foraminoscopic extraction of nucleus pulposus on lumbar disc herniation （LDH）. Methods In this study, 140 LDH patients who underwent percutaneous intervertebral foraminoscopic nucleus pulpotomy in our hospital from January 2021 to December 2023 were selected as the minimally invasive group, and 140 LDH patients who underwent laminary-fenestration nucleus pulpotomy in our hospital at the same time period were selected as the control group, and the therapeutic effects of the two groups were compared and analyzed. Results The operative time, intraoperative blood loss, and the first time to get out of bed in the minimally invasive group were significantly less than those in the control group （P<0.05）. There was no significant difference in the total effective rate between the two groups （P>0.05）. The complication rate of the minimally invasive group was significantly lower than that of the control group （P<0.05）. Before surgery, the visual analog scale （VAS） scores, 36-time short-form survey （SF-36） scores, Oswestry disability index （ODI）, Japanese Orthopaedic Association （JOA） scores, lumbar lordosis angle, and lumbar bone inclination angle were not significantly different between the two groups （P>0.05）. After surgery, the pain level （VAS score reduced）, lumbar spine function （ODI reduced, and JOA score increased）, spinal stability （lumbar lordosis angle and lumbar bone inclination angle both increased）, and quality of life （SF-36 score increased） were significantly improved in the two groups compared with before surgery （P<0.05）. Postoperative SF-36 score, lumbar lordosis angle, and lumbar bone inclination angle in the minimally invasive group were significantly better than those in the control group （P<0.05）, but there was no significant difference in VAS, ODI, and JOA scores between the two groups （P>0.05）. Conclusion Compared with fenestration of laminae, percutaneous foraminoscopic extraction of nucleus pulposus for the treatment of LDH can significantly shorten operation time, promote postoperative recovery, improve spinal stability and patients' quality of life, and significantly reduce the occurrence of postoperative complications, so it can be popularized. References | Related Articles | Metrics

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Impact of perioperative respiratory guidance on lung function and complications in patients undergoing thoracoscopic lung cancer resection CHEN Fangshuo, CHEN Jianming 2025, 14 (3):  248-252.  doi: 10.3969/j.issn.2095-378X.2025.03.011 Abstract ( 21 )   PDF (1353KB) ( 38 )   Save Objective To investigate the effect of perioperative respiratory guidance on lung function and complications in patients undergoing thoracoscopic lung cancer resection. Methods This study selected 80 perioperative patients undergoing thoracoscopic lung cancer resection from February 2021 to July 2024. The study subjects were divided into a control group and an observation group using a random number table method, with 40 cases in each group. The control group received routine nursing interventions, while the observation group received respiratory guidance on the basis of the control group. Lung function indicators after invervention, postoperative recovery indicators, and incidence of complications were compared between the two groups. Results Before intervention, there was no significant difference in pulmonary function indexes [forced expiratory volume in 1 s （FEV1）, vital capacity （VC）, and forced vital capacity （FVC）] between the two groups. After intervention, the lung function indicators of the observation group were significantly higher than those of the control group （P<0.05）. The observation group had significantly lower postoperative exhaust time and initial out-of-bed time than the control group （P<0.05）. The incidence of complications in the observation group was only 7.50%, lower than 32.50% in the control group （χ2=7.813,P<0.05）. Conclusion Respiratory guidance during the perioperative period for patients undergoing thoracoscopic lung cancer resection can improve their lung function while reducing the incidence of complications, which has clinical significance. References | Related Articles | Metrics

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Evaluation of efficacy and safety of laparoscopic common bile duct exploration and primary suture in treatment of choledocholithiasis JIANG Xiaojie, LIAO Changxi, LIN Wei, CAI Qinghe 2025, 14 (3):  253-256.  doi: 10.3969/j.issn.2095-378X.2025.03.012 Abstract ( 20 )   PDF (1323KB) ( 25 )   Save Objective To investigate the efficacy and safety of laparoscopic common bile duct exploration （LCBDE） and primary suture in the treatment of choledocholithiasis. Methods A total of 220 patients with choledocholithiasis treated with LCBDE from June 2022 to May 2024 were selected as study subjects, and randomly divided into a primary suture group （124 cases） and a T-tube drainage group （96 cases）. The efficacy of the two groups was compared. Results The operation time, postoperative drainage time, hospital stay, postoperative ambulation time, and gastrointestinal function recovery time of the primary suture group were significantly shorter than those of the T-tube drainage group （P<0.05）. The amount of blood loss during operation was not different between the two groups （P>0.05）. Before operation, the bilirubin indexes were not different between the two groups （P>0.05）; at postoperative 3 d, the bilirubin indexs of the two groups were significantly reduced compared with before operation, and the indexes in the primary suture group were lower than those in the T-tube drainage group （P<0.05）. The complication rate of the primary suture group was significantly lower than that of the T-tube drainage group （P<0.05）. After 6 months of follow-up, no recurrence of stones was found by choledochoscopy. Conclusion Compared with T-tube drainage, the application of primary suture in LCBDE has better clinical effect and higher safety, which is conducive to the rehabilitation of patients. References | Related Articles | Metrics

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Impact of endoscopic thyroidectomy by gasless trans-subclavian approach on cosmetic satisfaction and complications in patients with papillary thyroid carcinoma LIN Chaoyang, WANG Gang, ZHANG Nianqing 2025, 14 (3):  257-261.  doi: 10.3969/j.issn.2095-378X.2025.03.013 Abstract ( 18 )   PDF (1413KB) ( 2 )   Save Objective To investigate the impact of endoscopic thyroidectomy by gasless trans-subclavian approach （ETGTA） on cosmetic satisfaction and complications in patients with papillary thyroid carcinoma （PTC）. Methods A total of 80 PTC patients diagnosed and treated from January 2022 to December 2024 were selected. Among them,48 patients who underwent traditional open surgery combined with central lymph node dissection were included in the control group, and 32 patients who underwent ETGTA combined with central lymph node dissection were included in the study group. Surgical indicators, cosmetic satisfaction, and complications were observed in both groups. Results Compared with the control group,patients in the study group had longer operative time, greater postoperative drainage volumes, higher cosmetic satisfaction, and a lower incidence of neck discomfort （P<0.05）. No statistically significant differences were observed between the two groups in the incidence of recurrent laryngeal nerve injury and hypoparathyroidism （P>0.05）. Conclusion For PTC patients,ETGTA demonstrates significant efficacy, high safety, and excellent cosmetic outcomes. References | Related Articles | Metrics

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Effect of remimazolam or propofol combined with alfentanil intravenous anesthesia on vital signs of patients undergoing painless gastrointestinal endoscopy ZHU Chuanlin, LIU Yong, WANG Chaozhong, CHEN Tingting 2025, 14 (3):  262-265.  doi: 10.3969/j.issn.2095-378X.2025.03.014 Abstract ( 21 )   PDF (1371KB) ( 10 )   Save Objective To evaluate the value of intravenous anesthesia with remimazolam or propofol combined with alfentanil in painless gastrointestinal endoscopy. Methods A total of 100 patients who underwent painless gastrointestinal endoscopy at the First Hospital of Danjiangkou City, Hubei Province were randomly selected from January 2023 to January 2025. According to anesthesia regimens, they were divided into two groups, with 50 cases in each group. The control group was given intravenous anesthesia with propofol combined with alfentanil, while the observation group was administered intravenous anesthesia with remimazolam combined with alfentanil. The vital signs [systolic blood pressure （SBP）, diastolic blood pressure （DBP）, heart rate （HR）, and blood oxygen saturation （SpO2）], clinical indicators （anesthesia induction time, examination time, and awakening time）, and adverse reactions were compared between the two groups. Results After implementing different intravenous anesthesia regimens, the SBP, DBP, and HR values at 5 min of examination （T2） and at the end of examination （T3）, as well as the SpO2 at T2, were more stable in the observation group than those in the control group. The anesthesia induction time, examination time, and awakening time were shorter, and the overall incidence of adverse reactions was lower in the observation group than in the control group （P<0.05）. Conclusion For painless gastrointestinal endoscopy, the use of remimazolam combined with alfentanil for intravenous anesthesia has a high application value and is worth promoting. References | Related Articles | Metrics

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Effect of nerve block combined with pulsed radiofrequency on postherpetic neuralgia YU Xianhua, LI Yangmin 2025, 14 (3):  266-269.  doi: 10.3969/j.issn.2095-378X.2025.03.015 Abstract ( 23 )   PDF (1301KB) ( 13 )   Save Objective To investigate the efficacy of nerve block combined with pulsed radiofrequency in the treatment of postherpetic neuralgia （PHN）. Methods A total of 100 PHN patients treated from January 2022 to December 2024 were selected as research subjects and randomly divided into a nerve block group （paravertebral nerve block） and a combined treatment group （paravertebral nerve block combined with pulsed radiofrequency）, with 50 cases in each group. The effects between the two groups were compared. Results Before treatment, there was no significant difference in visual analog scale （VAS）, pain rating index （PRI）, and present pain intensity （PPI） scores between the two groups （P>0.05）. The VAS, PRI, and PPI scores of both groups were significantly reduced after treatment （7 d and 30 d） （P<0.05）, and the scores in the combined treatment group were lower than those in the nerve block group （P<0.05）. Before treatment, there were no significant differences in self-rating anxiety scale （SAS）, self-rating depression scale （SDS）, Pittsburgh sleep quality index （PSQI）, and short-form 36 （SF-36） scores between the two groups （P>0.05）. At 30 d after treatment, the SAS, SDS, PSQI, and SF-36 scores of the two groups were significantly improved （SAS, SDS, and PSQI scores were reduced, while SF-36 scores were imcreased） （P<0.05）, and the scores in the combined treatment group were significantly better than those in the nerve block group （P<0.05）. The total effective rate of treatment of the combined treatment group was significantly higher than that of the nerve block group （P<0.05）. Conclusion Nerve block combined with pulse radiofrequency in the treatment of PHN can significantly alleviate pain of patients and improve treatment efficacy, which meets clinical needs and can be popularized. References | Related Articles | Metrics

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Application value of general anesthesia combined with iliaca fascia nerve block in total hip arthroplasty LIU Fang, WU Zhiwei, XIE Yao 2025, 14 (3):  270-273.  doi: 10.3969/j.issn.2095-378X.2025.03.016 Abstract ( 16 )   PDF (1294KB) ( 20 )   Save Objective To evaluate the application value of general anesthesia combined with iliac fascia nerve block in total hip arthroplasty. Methods A total of 80 patients who underwent elective total hip arthroplasty from January 2022 to December 2023 were selected as study subjects, and randomly divided into an observation group （40 cases, general anesthesia combined with iliac fascia nerve block） and a control group （40 cases, general anesthesia）, and the efficacy of the two groups was compared. Results The pain scores of the observation group at 2, 6, 12 and 24 h postoperaitvely were significantly lower than those of the control group （P<0.05）. Before anesthesia, the hemodynamic indexes of the two groups were not statistically different （P>0.05）. At the time of intubation, 30 min after operation, and at the time of extubation, the hemodynamic variations of the observation group were significantly lower than those of the control group （P<0.05）. The incidence of adverse reactions between the two groups were not different （P>0.05）. Conclusion The application of general anesthesia combined with iliac fascia nerve block in total hip arthroplasty can achieve stable hemodynamic indexes while not increase adverse reactions. References | Related Articles | Metrics

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Application of quality control circle activities in quality management of color ultrasonic diagnostic equipment LU Sijie, ZHENG Jiaxin, YAN Hao, ZHU Zhigang 2025, 14 (3):  274-279.  doi: 10.3969/j.issn.2095-378X.2025.03.017 Abstract ( 13 )   PDF (2054KB) ( 31 )   Save Against the backdrop of national fertility policy adjustments, Shanghai First Maternity and Infant Hospital ranks among the top in annual delivery volumes nationwide. As a core device for prenatal screening, the quality control of color ultrasonic diagnostic equipment directly impacts fetal anomaly detection rates and clinical safety. To address this, we established the "Pregnancy Eye Circle" quality control circle （QCC）, integrating 9 multidisciplinary members including biomedical engineers, quality controllers, and clinicians （circle competence score： 80%）. Focusing on "improving the pass rate of color ultrasonic diagnostic equipment quality control inspections", we defined 5 critical performance indicators （e.g., maximum depth and resolution） as mandatory compliance standards. Utilizing the PDCA-SDCA dual-loop model and seven QCC tools, we systematically addressed the pass rate deficiency （baseline 41%）. Through image quality factor analysis, standardized training programs, and process optimization implementation, we conducted full-cycle quality monitoring on 34 ultrasound systems, achieving an upgraded pass rate of 81.8% （target attainment ratio： 104.1%; improvement rate： 99.5%）. This project demonstrated significant enhancements in equipment quality control efficiency, established an integrated medical-engineering-clinical quality management framework, and strengthened multidisciplinary collaboration capabilities. Future initiatives will focus on refining preventive maintenance protocols and advancing lifecycle management for medical devices. References | Related Articles | Metrics

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Construction and empirical study of multidimensional management system of medical consumables based on HRP system LU Qiang, ZHOU Yang 2025, 14 (3):  280-284.  doi: 10.3969/j.issn.2095-378X.2025.03.018 Abstract ( 18 )   PDF (1544KB) ( 31 )   Save Objective To establish a multidimensional management system of medical consumables（MMM-MCM） based on hospital resource planning （HRP） system and validate its operational efficacy. MethodA four-dimensional management framework was constructed encompassing quality control [unique device identifier（UDI） traceability], cost optimization （ABC-VEN classification）, operational efficiency （dynamic inventory）, and risk mitigation （integrity early-warning）.A prospective intervention research method was used to analyze the hospital consumables data （1 236 589 items） from 2020 to 2024, and a difference-in-difference （DID） model was used to analyze the management efficiency before and after the implementation of MMM-MCM. Results Post-implementation outcomes demonstrated 35.1% improvement in comprehensive management score （92.3±3.1） compared with baseline （P<0.001）. Specifically, （1） the inventory turnover increased by 38.7% with acceptance error rate reduced to 0.9%; （2） the supplier license completeness reached 99.6% with 28.5% higher delivery punctuality;（3）high-value consumables cost accounting errors decreased to 2.1%, freeing up ¥21 million capital. Conclusion The MMM-MCM model significantly enhances standardization in medical consumables management after innovatively integrating the HRP system with the whole-life management of medical consumables, providing a replicable paradigm for hospital lean operations. References | Related Articles | Metrics

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Design and development of the digital management platform for consumables intelligence HAN Zhaojin 2025, 14 (3):  285-288.  doi: 10.3969/j.issn.2095-378X.2025.03.019 Abstract ( 15 )   PDF (1621KB) ( 29 )   Save Objective To design a smart digital management platform for consumables, which can achieve effective integration and collaboration among internal and external systems [including the Hospital Information System （HIS）, Shanghai Sunshine Procurement Platform, intelligent equipment, Supply, Processing, and Distribution（SPD） manufacturers, and clinical departments], and effectively realize functions such as application, procurement, distribution, acceptance, inventory entry and exit, and supervision of consumables, as well as data collection, organization, statistics, and utilization. This is to achieve hospital refined management and reduce operating costs. Methods By analyzing the current situation and demands of hospital material management, and based on the division of hospital functional departments and internal control management system, the system module functions and business processes were designed and described in detail. Results and Conclusion A smart digital management platform for consumables was developed, and effectively achieved full-process traceability management for consumables from application, procurement, distribution, acceptance, inventory entry and exit, use, and supervision throughout the hospital internal and external processes. References | Related Articles | Metrics

Nursing

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Application effect of humanized nursing intervention combined with position management in thoracoscopic mediastinal tumor resection QIN Xiaoyun, WEN Quan, XU Hongkun, ZHOU Liyan 2025, 14 (3):  289-293.  doi: 10.3969/j.issn.2095-378X.2025.03.020 Abstract ( 14 )   PDF (1305KB) ( 18 )   Save Objective To explore the intervention effect of humanized nursing intervention combined with position management on patients undergoing thoracoscopic mediastinal tumor resection. Methods Data of 84 patients who underwent thoracoscopic resection of mediastinal tumor from April 2021 to June 2023 were retrospectively analyzed. Among them, 42 patients who underwent routine intervention and position management intervention were included in the control group, and 42 patients who received humanized intervention on the basis of position management were included in the observation group. Before intervention and at 24 h and 48 h of intervention, the nursing compliance （using the self-made nursing compliance scale）, pain levels [using the numerical rating scale （NRS）], and postoperative rehabilitation indicators （time to get out of bed, time of thoracic drainage tube retention, and length of hospital stay） of the two groups were assessed and compared. Results The compliance scores of both groups of patients at 24 h and 48 h of intervention were higher than those before intervention, and the scores of the observation group were higher than those of the control group （P<0.05）. The NRS scores of both groups of patients at 24 h and 48 h of intervention decreased compared to before intervention, and the scores of the observation group were lower than those of the control group （P<0.05）. There was no significant difference in the time to get out of bed, retention time of thoracic drainage tube, and length of hospital stay between the two groups （P>0.05）. Conclusion The application of humanized intervention combined with position management in patients undergoing thoracoscopic mediastinal tumor resection can improve their compliance with position management and help alleviate postoperative pain. References | Related Articles | Metrics

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Qualitative study of knowledge of full-cycle rehabilitation of heat stroke among ICU medical staff YU Qingling, HUANG Xiuli, ZHU Xiumei 2025, 14 (3):  294-298.  doi: 10.3969/j.issn.2095-378X.2025.03.021 Abstract ( 16 )   PDF (1243KB) ( 14 )   Save Objective To understand the knowledge and practice of full-cycle rehabilitation of heat stroke among intensive care unit （ICU） medical staff, reveal their confusion, challenges, and needs at work, and provide theoretical support for optimizing clinical management and rehabilitation services of patients with heat stroke. Methods Using the phenomenological research method, a semi-structured interview was conducted with 15 medical staff in the Emergency Medicine Department from June to August 2024. The data were analyzed with Colaizzi seven procedural steps and the theme was revealed. Results The ICU medical staff had cognitive differences in the full-cycle rehabilitation of heat stroke, especially in the timing of rehabilitation, and attached great importance to psychological support. The respondents had significant individual differences in their understanding of heat stroke rehabilitation strategies, hold different views on when to start rehabilitation, and generally agreed with the core position of psychological support in patients' rehabilitation process. Conclusion The study findings emphasize the practical problems and needs of the full-cycle rehabilitation of heat stroke based on the perspective of ICU medical staff, which has important theoretical and practical significance for improving the overall rehabilitation effect of patients. These findings contribute to improved prognosis and quality of life in patients with heat stroke and provide key insights into improved clinical practice and improved quality of rehabilitation services. References | Related Articles | Metrics