Table of Content

28 March 2020, Volume 9 Issue 1 Previous Issue    Next Issue

Original article

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Factors influencing complete response rate of liver cancer after percutaneous radiofrequency ablation LIU Congcong, SHI Baomin 2020, 9 (1):  1-5.  doi: 10.3969/j.issn.2095-378X.2020.01.001 Abstract ( 98 )   PDF (1019KB) ( 327 )   Save Objective To explore the factors influencing the complete response (CR) rate of liver cancer after percutaneous radiofrequency ablation (PRFA). Methods A total of 60 patients with liver cancer treated with ultrasound-guided PRFA were recruited from our hospital. According to the postoperative results of contrast-enhanced ultrasound, the patients were divided into CR group and in-complete response (ICR) group. The ablation number of lesions and CR rate under the influence of different factors were recorded and the differences of each factor between the two groups were compared. Further multiple logistic regression was used to analyze the independent influencing factors of tumor CR rate after PRFA. Results A total of 94 lesions were completely ablated after PRFA treatment, and the total CR rate was 91.26%. Tumor type, special anatomical position, maximum tumor diameter, ablative margin, ablation energy, and central temperature were significantly correlated with the CR rate of tumor (P<0.05). Further multiple logistic regression results showed that tumor type (P=0.024), special anatomical position (P=0.031), maximum tumor diameter (P=0.001), ablative margin (P<0.001), ablation energy (P=0.003) and central temperature of tumor (P=0.009) were independent influencing factors of tumor CR rate after PRFA. Conclusion Tumor type, special anatomic location, maximum tumor diameter,ablative margin, ablation energy, and central temperature of tumor have important effects on CR rate of liver cancer after PRFA. References | Related Articles | Metrics

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Factors of non-sentinel lymph node metastasis in 98 early breast cancer patients WU Songling, ZHANG Meize, LIU Jiahui, ZHAN Qiaohui 2020, 9 (1):  6-9.  doi: 10.3969/j.issn.2095-378X.2020.01.002 Abstract ( 159 )   PDF (545KB) ( 299 )   Save Objective To provide reference for the development of individualized treatment regime for axillary lymph node by analyzing sentinel lymph node (SLN) and selected clinical and pathological characteristics of that may affect non-sentinel lymph node (NSLN) metastasis during early breast cancer. Methods The clinical and pathological data of early breast cancer patients with sentinel lymph node biopsy (SLNB) positive and who further received axillary lymph node dissection (ALND) in the Second Affiliated Hospital of Xiamen Medical College from March 2015 to December 2018 were retrospectively analyzed. Univariate analysis and multiple logistic regression analysis were applied to analyze the relationships between these clinicopathological factors and NSLN metastasis. Results According to the inclusion and exclusion criteria, a total of 98 cases were enrolled in the study. Among them, 33 (33.7%) patients had NSLN metastasis. The results of univariate analysis showed that histological grade (P=0.021), ≥3 positive SLN metastasis (P=0.013), and lymph-vascular invasion (P<0.001) were associated with NSLN metastasis. The results of multiple logistic analysis revealed that lymph-vascular invasion was an independent predictor for NSLN metastasis. Conclusion Histological grade, the number of positive SLN, and lymph-vascular invasion are correlated with NSLN metastasis. Lymph-vascular invasion may be an important independent predictor for NSLN metastasis. References | Related Articles | Metrics

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Application value of fecal SDC2 gene methylation test in early colorectal tumor diagnosis LI Chuangkun, HUANG Yingfeng, ZOU Liaonan, LI Xiaoying, LUO Jie, NIU Feng, ZHAO Risheng, WANG Huaiming, WANG Hui, HUANG Rongkang 2020, 9 (1):  10-13.  doi: 10.3969/j.issn.2095-378X.2020.01.003 Abstract ( 178 )   PDF (547KB) ( 442 )   Save Objective To investigate the value of fecal SDC2 gene methylation test in early colorectal tumor diagnosis. Methods Medical records data of 134 enrolled patients were collected from six hospitals from January 2018 to December 2018. The sensitivity and specificity between fecal SDC2 gene methylation test and serum carcinoembryonic antigen (CEA) test for early colorectal tumor diagnosis were compared. Results Of the 134 enrolled cases, 86 cases were without colorectal tumors, 22 cases with colorectal adenoma, and 26 cases with colorectal cancer. Fecal SDC2 gene methylation was detected positive in 45 patients and negative in 89 patients. Serum CEA was detected positive in 16 patients and negative in 118 patients. In the 26 patients with colorectal cancer, the positive rate of SDC2 gene methylation (88.46%) was higher than that of serum CEA (27.59%), indicating that the sensitivity of SDC2 gene methylation test was higher than that of serum CEA test for patients with colorectal cancer (P<0.001). In the 22 patients with colorectal adenoma, the positive rate of SDC2 gene methylation was higher than that of serum CEA (22.73% vs. 4.54%, P=0.185). Conclusion Compared with serum CEA test, fecal SDC2 gene methylation test has a higher sensitivity in the diagnosis of colorectal tumor and precancerous lesions, and its role in the early diagnosis of colorectal tumor requires to be investigated in a larger sample size. References | Related Articles | Metrics

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Observation of short-term effect of laparoscopic radical operation for colorectal cancer YANG Xiuchun, WANG Pan 2020, 9 (1):  14-16.  doi: 10.3969/j.issn.2095-378X.2020.01.004 Abstract ( 108 )   PDF (559KB) ( 490 )   Save Objective To observe the short-term effect of laparoscopic radical operation for colorectal cancer. Methods Thirty-six patients with colorectal cancer undergoing laparoscopic radical surgery from January 2016 to January 2019 were selected as laparoscopic group, and 22 patients with colorectal cancer undergoing open radical surgery at the same time were selected as laparotomy control group. The short-term therapeutic effects between the two groups were compared and analyzed. Results Longer operation time, less intraoperative blood loss, shorter postoperative first exhaust time, and shorter feeding time in the laparoscopic group were observed than those in the laparotomy group (P<0.05). No differences in the number of lymph node dissection and the length of distal end of tumor between the two groups were observed. The levels of serum IL-6 and IL-8 in the laparotomy group was significantly higher than those in the laparoscopic group. Conclusion Laparoscopic radical operation is as effective as laparotomy, but less invasive and safer for colorectal cancer. References | Related Articles | Metrics

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Observation of effect of intraperitoneal perfusion during laparoscopic radical gastrectomy on advanced gastric cancer PAN Jianhai, LI Zhongmin, HUA Jiancan 2020, 9 (1):  17-19.  doi: 10.3969/j.issn.2095-378X.2020.01.005 Abstract ( 159 )   PDF (567KB) ( 314 )   Save Objective To observe the effect of intraperitoneal perfusion during laparoscopic radical gastrectomy on advanced gastric cancer. Methods Eight two patients with advanced gastric cancer undergoing laparoscopic radical gastrectomy were randomly divided into a control group (n=41) and an observation group (n=41) by random number table method. The control group received laparoscopic radical gastrectomy only, and the observation group received laparoscopic radical gastrectomy and intraoperative intraperitoneal perfusion. The therapeutic effects were compared between the two groups. Results The postoperative drainage time, hospitalization time, and disease recurrence rate after 12 months of the observation group were shorter and lower than those of the control group (P<0.05); but no significant differences in operation time, intraoperative blood loss volume, postoperative exsufflation time, postoperative complication and side effect rates, and disease recurrence after 6 months were observed between the two groups. Conclusion Intraperitoneal perfusion during laparoscopic radical gastrectomy for advanced gastric cancer is safe and effective, can shorten hospitalization time and delay recurrence, and is worth promoting. References | Related Articles | Metrics

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Evaluation of effect of non-dissected Roux-en-Y anatomosis on digestive tract reconstruction after laparoscopic resection for distal gastric cancer CHEN Kai, WU Zuguang, YAO Shiwei, DENG Xueyong, LIU Zhanying 2020, 9 (1):  20-21.  doi: 10.3969/j.issn.2095-378X.2020.01.006 Abstract ( 121 )   PDF (540KB) ( 469 )   Save Objective To evaluate the clinical effect of non-dissected Roux-en-Y anastomosis on laparoscopic radical gastrectomy for distal gastric cancer and digestive tract reconstruction. Methods A total of 80 patients with gastric cancer who underwent laparoscopic radical gastrectomy from January 2014 to December 2018 were divided into non-dissected Roux-en-Y anastomosis group (observation group, 40 cases) and Billroth II anastomosis group (control group, 40 cases) according to digestive tract reconstruction methods. The surgical indicators, postoperative exsufflation time, complication rate, and hospitalization stay were compared between the two groups. Results The intraoperative bleeding amount and operation duration of the observation group were more than those of the control group (P<0.01), but no significant differences in complication rate and hospitalization time were observed between the two groups. Conclusion Non-dissected Roux-en-Y anastomosis is effective and safe in laparoscopic radical gastrectomy for distal gastric cancer and digestive tract reconstruction. References | Related Articles | Metrics

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Influences of different knee joint prosthesis types on limb function recovery after initial and unilateral knee arthroplasty YANG Weiqing, TANG Ceyang, FENG Huajie 2020, 9 (1):  22-24.  doi: 10.3969/j.issn.2095-378X.2020.01.007 Abstract ( 139 )   PDF (560KB) ( 304 )   Save Objective To compare the clinical efficacy of cruciate retaining and posterior stablized prosthesis during initial and unilateral knee arthroplasty, as well as their influences on limb swelling and limb function recovery. Methods A total of 160 knee osteoarthritis patients who underwent total knee arthroplasty from December 2016 to December 2018 were selected and assigned to cruciate retaining group and posterior stablized group according to knee joint prosthesis types, with 80 cases in each group. Patients adopted initial and unilateral knee arthroplasty with cruciate retaining and posterior stablized prosthesis, respectively. Their postoperative serum inflammatory response, limb function recovery, and clinical efficacy were assessed. Results After respective treatments, the serum C-reactive protein and IL-6 levels of the two groups were lower than before (P<0.05). The knee joint function scores of the two groups after respective treatments were higher than before (P<0.05). The knee joint function scores of the cruciate retaining group 3 and 6 months after discharge were higher than those of the posterior stablized group (P<0.05). Conclusion During initial and unilateral knee arthroplasty, the cruciate retaining prosthesis can improve limb function and reduce serum inflammatory response. References | Related Articles | Metrics

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Surgical treatment for congenital constriction band syndrome CAO Jiang, YU Song, YANG Xiaohong, LYU Xin 2020, 9 (1):  25-27.  doi: 10.3969/j.issn.2095-378X.2020.01.008 Abstract ( 127 )   PDF (7091KB) ( 214 )   Save Objectives To introduce the surgical treatment experience of congenital constriction band syndrome. Methods From July 2013 to November 2018, nine children with congenital constriction band syndrome adopted stage-one surgical removal of the band and Z-plasty, among which two cases of lower leg band combined with talipes equinovarus additionally received extensive soft tissue release of talipes equinovarus and tendon transfer operation based on Ponseti plaster therapy one year later. Results All the surgical incisions of the nine cases healed well, no flap necrosis occurred, and the annular constricted narrow bands were fully released. The surgical effects for the two cases of lower leg band combined with talipes equinovarus were satisfactory without recurrence. Conclusion Stage-one surgical removal of the band and release of the soft tissue will not lead to necrosis of the skin flap, and can obtain a satisfactory appearance. Extensive soft tissue release and tendon transfer of talipes equinovarus based on Ponseti plaster treatment is an excellent surgical method for the treatment of constriction band combined with talipes equinovarus. References | Related Articles | Metrics

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Efficacy comparison of two different flap free methods performed in endoscopic thyroidectomy WU Weiwen, ZHEN Jiesheng, YUAN Chaojie, CHENG Jian 2020, 9 (1):  28-30.  doi: 10.3969/j.issn.2095-378X.2020.01.009 Abstract ( 130 )   PDF (557KB) ( 360 )   Save Objective To compare the efficacy and safety of endoscopic scissors plus ultrasonic scalpel and ultrasonic scalpel only to free flap during endoscopic thyroidectomy. Methods A total of 128 patients were randomly divided into two groups, including 60 cases using endoscopic scissors plus ultrasonic scalpel and 68 cases using ultrasonic scalpel only. The free flap time, gas consumption, blood loss, and subcutaneous drainage 48 h after surgery were recorded for both groups. Postoperative follow-up was conducted 1 month after the surgery to record patients' local skin paresthesia. Results All surgeries were performed well. No significant differences were found between the two groups in the amount of blood loss, subcutaneous drainage at 48 h, and local flap paresthesia after 1 month (P> 0.05). However, the free flap time and gas consumption were significantly different (P<0.05). Conclusion The reasonable application of endoscopic scissors plus ultrasonic scalpe can expand the operating space for endoscopic thyroidectomy rapidly, especially for the free flap of thoracic region. Meanwhile, it can reduce the amount of gas consumption and shorten the time of free flap, without increasing the amount of intraoperative blood loss and subcutaneous drainage 48 h after surgery. This method is safe and effective, thus it is worth popularizing. References | Related Articles | Metrics

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Curative effects of continuous suture and interrupted suture after autologous conjunctival transplantation for pterygium QIU Zhihua, ZHU Jing 2020, 9 (1):  31-34.  doi: 10.3969/j.issn.2095-378X.2020.01.010 Abstract ( 131 )   PDF (616KB) ( 263 )   Save Objective To explore the effects of continuous suture and interrupted suture on corneal healing, pain degree, and tear film stability after autologous conjunctival transplantation for pterygium. Methods A total of 86 patients who underwent resection of pterygium and autologous conjunctival transplantation of corneal limbal stem cells from January 2017 to January 2019 were retrospectively analyzed. According to suture methods, the patients were assigned to continuous suture group (n=43) and interrupted suture group (n=43). The corneal healing degree, visual analogue scale score, and tear film stability were compared between the two groups. Results The visual analogue scale score, corneal healing degree, and tear film stability in the continuous suture group were better than those in the interrupted suture group (P<0.05). Conclusion After resection of pterygium and autologous conjunctival transplantation, continuous suture can improve corneal healing degree, relieve pain, and produce less impact on tear film stability. References | Related Articles | Metrics

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Application of Ruiyun procedure for hemorrhoid plus Diosmin in treatment of mixed hemorrhoid HUANG Qihao 2020, 9 (1):  35-38.  doi: 10.3969/j.issn.2095-378X.2020.01.011 Abstract ( 248 )   PDF (588KB) ( 403 )   Save Objective To evaluate the effect of Ruiyun procedure for hemorrhoid (RPH) plus Diosmin on mixed hemorrhoid. Methods Eighty mixed hemorrhoid patients treated from January 2019 to September 2019 in our hospital were assigned to a regular surgery group and a combined surgery group (regular surgery combinded with RPH) by stratified sampling method, with 40 cases in each group. The curative effects were probed in the two groups. Results The total effective rate in the combined surgery group (92.5%) was significantly higher than that in the regular surgery group (P<0.05). Before treatment, the tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and C-reactive protein (CRP) levels between the two groups were not significantly different (P>0.05); after treatment, the levels of above inflammatory factors in the two groups were remarkably reduced than before (P<0.05), and the levels in the combined surgery group were lower then those in the regular surgery gronp (P<0.05). The complication rate in the combined surgery group (7.5%) was significantly lower than that in the regular surgery group (25%)(P<0.05). Conclusion RPH combined with Diosmin applied for mixed hemorrhoid can obviously improve treatment effects by alleviating clinical symptoms and reducing the levels of inflammatory factors and inflammatory responses. References | Related Articles | Metrics

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Application value of CBCT in oral surgical extraction of impacted teeth YANG Hua 2020, 9 (1):  39-41.  doi: 10.3969/j.issn.2095-378X.2020.01.012 Abstract ( 142 )   PDF (510KB) ( 825 )   Save Objective To observe the practical application of cone beam CT (CBCT) in the examination of patients with oral surgical impacted tooth extraction. Methods A total of 56 patients with impacted tooth extraction who were admitted to our hospital from August 2017 to August 2019 were selected as study subjects. They were randomly divided into control group (routine examination) and experimental group (CBCT examination). The treatment effect, occurrence of adverse reactions, and patient's satisfaction with the examination were compared between the two groups. Results The overall effect of the experimental group was obviously better, the adverse reactions were fewer, and patients’ overall satisfaction were higher in the experimental group than in the control group (P <0.01). Conclusion For patients undergoing extraction of impacted teeth, CBCT examination can produce satisfying effects and the method is worthy of clinical promotion. References | Related Articles | Metrics

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Arthroscopic-assisted channel expansion in the treatment of secondary popliteal cyst LIU Zhihua 2020, 9 (1):  42-45.  doi: 10.3969/j.issn.2095-378X.2020.01.013 Abstract ( 115 )   PDF (1729KB) ( 377 )   Save Objective To study the effect of arthroscopic-assisted channel expansion on secondary popliteal cyst. Methods A total of 100 patients with secondary popliteal cyst patients were investigated from January 2016 to January 2019 and randomly divided into a control group (n=50) and an observation group (n=50). The control group took conventional resection of posterior popliteal cyst; the observation group took the arthroscopic debridement under local anesthesia, channel expansion between cyst and articular cavity, and preservation of cyst wall. Hospital stays and overall treatment effective rate were compared. Results Hospital stays in the observation group were shorter than those in the control group (P<0.05); overall treatment effective rate in the observation group was higher than that in the control group (P<0.05). Conclusion Arthroscopic-assisted channel expansion can preserve cyst wall, reduce clinical trauma and hospital stays, and increase surgical effects. References | Related Articles | Metrics

Review

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Research progress on postpartum stress urinary incontinence treated by traditional Chinese medicine TANG Hong, ZHANG Yu, WANG Jun 2020, 9 (1):  46-49.  doi: 10.3969/j.issn.2095-378X.2020.01.014 Abstract ( 159 )   PDF (646KB) ( 695 )   Save Postpartum stress urinary incontinence is an involuntary urine outflow through urethra in women with postpartum abdominal pressure increase, which seriously affects women's physical and mental health and quality of life. This paper summarized and analyzed the research progress on postpartum stress urinary incontinence treated by traditional Chinese medicine from the aspects of etiology and pathogenesis, traditional Chinese materia medica treatment, acupuncture treatment, and other external treatment. Traditional Chinese medicine combined with rehabilitation has a significant effect on postpartum stress urinary incontinence, but there are still some shortages in current research to be improved. References | Related Articles | Metrics

Medical instrument

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Reconstruction and application of material budget management and control based on hospital intelligent platform YANG Xiaoqiu, GE Xin 2020, 9 (1):  50-53.  doi: 10.3969/j.issn.2095-378X.2020.01.015 Abstract ( 111 )   PDF (2766KB) ( 387 )   Save Objective To realize the reasonable allocation of logistics and capital flow, and strengthen the budget management of material procurement in hospitals through the management and control of departmental material budget. Methods Through Webservice, the established hospital intelligent platform was connected with a material management system to realize data interaction. Alerts were set to control the bugdet of each department. Results Through docking with the hospital intelligent platform, our hospital realized monitoring and managing the use of material budget in all departments, and presenting budget control report forms to hospital managers. Conclusion With the implementation of comprehensive budget management in public hospitals, hospital material budget management has become one of the important links. Only by strictly controlling material budget can we achieve the goal of fine cost management in hospitals. References | Related Articles | Metrics

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Management practice of medical equipments on digital information platform of hospital materials ZHOU Haoyang, TANG Ronggao, YANG Jie 2020, 9 (1):  54-58.  doi: 10.3969/j.issn.2095-378X.2020.01.016 Abstract ( 147 )   PDF (1397KB) ( 338 )   Save Objective To optimize the management of medical equipment using a digital information platform of hospital materials. Methods Each management module in medical equipment management was analyzed, and the results were discussed on the basis of practice. Results The management methods for improving the management efficiency of medical equipment were summarized. Conclusion Through the digital information platform of hospital materials, the management of hospital medical equipment can be effectively improved, which will play a positive role in the future development of the hospital. References | Related Articles | Metrics

Case report

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One case of Madelung's disease GU Li, YU Lei, ZHANG Yiqian, WANG Xinli 2020, 9 (1):  59-62.  doi: 10.3969/j.issn.2095-378X.2020.01.017 Abstract ( 141 )   PDF (2161KB) ( 409 )   Save Madelung's disease (MD) is a rare fat metabolism disorder that causes progressive, excessive, and symmetrical deposition of adipose tissues in the deep and superficial fascial spaces. According to the distribution of adipose tissues, Madelung's disease is generally divided into three types in clinical practice. This paper introduced one case of Madelung's disease type Ⅰand discussed its pathogenesis, diagnosis, and treatment methods to provide reference for clinical diagnosis and treatment. References | Related Articles | Metrics

Nursing

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Reduction of peritoneal dialysis-associated peritonitis by caregiving participatory self-management in patients with peritonitis SUN Xiaomin, ZHUANG Qin, WANG Hong, XU Fanglei 2020, 9 (1):  63-66.  doi: 10.3969/j.issn.2095-378X.2020.01.018 Abstract ( 95 )   PDF (570KB) ( 425 )   Save Objective To investigate the effect of caregiving participatory self-management on reducing pertioneal dialysis-associated peritonitis in patients with peritonitis. Methods A group of 125 patients with home-based peritoneal dialysis from January 2017 to December 2017 were enrolled into the observation group, and adopted routine outpatient follow-up and health education guidance. Another group of 130 patients with home-based peritoneal dialysis from January 2018 to December 2018 were enrolled into the experimental group, and received caregiving participatory self-management on the basis of routine outpatient follow-up and health education guidance. The incidence of pertioneal dialysis-associated peritonitis was compared between the two groups. Results The incidence of pertioneal dialysis-associated peritonitis was significantly decreased from 70.38 patient months to 101.84 patient months after the implementation of caregiving participatory self-management (P<0.05). The incidence rates of pertioneal dialysis-associated peritonitis due to operational and enterogenous causes were also significantly decreased from 9 cases (7.2%) to 2 cases (1.5%) and from 10 (8.0%) cases to 2 cases (1.5%) respectively (P<0.05). Conclusion The implementation of caregiving participatory self-management can improve patient compliance and standarded peritoneal dialysate replacement, reduce the incidence of pertioneal dialysis-associated peritonitis caused by inappropriate operation or enterogenous causes, and finally increase the survival rate and quality of life of the patients. References | Related Articles | Metrics

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Nursing intervention of postural compliance of patients undergoing vitreous silicone oil tamponade CAO Qian, YANG Haojun 2020, 9 (1):  67-69.  doi: 10.3969/j.issn.2095-378X.2020.01.019 Abstract ( 105 )   PDF (584KB) ( 404 )   Save Objective To evaluate the effect of nursing intervention on postural compliance of patients with vitreous silicone oil tamponade. Methods A retrospective analysis was performed on the clinical data of 50 patients with silicone oil tamponade in vitreous cavity from January 2019 to November 2019 to compare the effects of routine posture guidance and special posture nursing interventions. Results The duration of special posture in the study group was significantly longer than that in the control group at 1 d, 3 d, and 5 d after operation (P < 0.05). The incidence rate of postoperative complications in the study group was significantly lower than that in the control group (P < 0.05). The patients'satisfaction with nursing service in the study group was also significantly higher than that in the control group (P < 0.05). Conclusion Nursing interventions with special posture after vitreous cavity silicone oil tamponade could shorten the duration of special posture, reduce the occurrence of complications, and improve the satisfaction of patients, which is worthy of clinical application. References | Related Articles | Metrics

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Therapeutic effect and nursing interventions of minimally invasive surgery on hypertensive cerebral hemorrhage ZHOU Haijie 2020, 9 (1):  70-72.  doi: 10.3969/j.issn.2095-378X.2020.01.020 Abstract ( 94 )   PDF (559KB) ( 399 )   Save Objective To observe the therapeutic effect of minimally invasive surgery on hypertensive cerebral hemorrhage and relevant nursing interventions. Methods Fifty hypertensive cerebral hemorrhage patients treated from July to December 2018 were selected and assigned to two groups according to different nursing methods, with 25 cases in each group. All the patients received minimally invasive surgery; the subjects in the control group adopted routine nursing measures, and those in the study group adopted high-quality nursing interventions. The therapeutic effect, neurological deficit, and activity of daily living scale scores were compared between the two groups. Results Upon discharge from hospital, the neurological deficit and activity of daily living scale scores between the two groups were not significantly different (P>0.05); after 3 months and 6 months of follow-up visits, the neurological deficit scores in the study group were lower than the scores in the control group; the activity of daily living scale scores in the study group were higher than the scores in the control group; the total effective rate in the study group (92.00%) was higher than that in the control group (76.00%) (P<0.05). Conclusion For patients with minimally invasive surgery, high-quality nursing interventions can efficiently improve their activity of daily living, relieve neurological deficit, and achieve an obvious effect. It is worthy of application. References | Related Articles | Metrics